Sildenafil citrate, commonly known by the brand name, is a prescription-only medicine used to treat erectile dysfunction (ED) in adult men. It works by improving blood flow to the penis, helping to achieve and maintain an erection during sexual activity.
Sildenafil is available in 25mg, 50mg, and 100mg strengths.
Sildenafil has been shown to be effective in up to 80% of men with ED, with effects typically noticeable within 30 to 60 minutes, and lasting for up to 4–5 hours.
Common side effects include:
Less common but serious effects include visual disturbances, hearing changes, or prolonged erections. Seek medical attention if severe or persistent side effects occur.
Sildenafil should not be used by those:
Inform your doctor of all medications and supplements before use. Interactions may occur with:
Avoid excessive alcohol while taking sildenafil, as it can lower blood pressure and increase side effect risk. Use with caution if you have any heart-related conditions.
Sildenafil is available by prescription only in the UK.
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Last updated 14 September 2023
On 14 March 2023, the UK Medicines regulator approved an application to reclassify the erectile dysfunction medication Cialis. When marketed asCialis Together(tadalafil 10mg), it will be a ‘P’ (pharmacy) medication, and so available ‘over the counter’ in pharmacies – see. This follows the 2018, ‘P’ classification of (sildenafil 50mg) which has been available OTC, without a prescription, since then.
This decision is good news for men’s health …. Erectile dysfunction can be a debilitating condition, so it’s important men feel they have fast access to quality and legitimate care
Dr Laura Squire, MHRA’s Chief Officer for Healthcare, Quality and Access
Unfortunately, there is a strong black market in the UK for ED medicines, which are often unlicensed or counterfeit. UK Border Force and the MHRA seize millions of pounds of these fake products from criminals annually. This new classification of tadalafil 10mg will enable men who suffer from ED to obtain it safely from a local pharmacy.
Sanofi, the drug manufacturer, is expected to launch Cialis Together later in 2023. Cialis Together will be available to purchase in pharmacies without a prescription by men over 18 with erectile dysfunction. Cialis Together tablets will contain 10mg tadalafil and the maximum pack size will be 8 tablets. Other doses and pack sizes of Cialis and tadalafil will still be available on prescription through doctors and specially trained pharmacists. Before purchase in a pharmacy there must be an assessment with a pharmacist, who will check that Cialis Together is appropriate and safe, or whether consultation with a GP is necessary.
Men suffering with ED will have another treatment option with the convenience of purchasing it in their local pharmacy, including pharmacies found inside supermarkets (eg. Tesco, Asda, Sainsbury’s). The pharmacist will ask some health questions, may check blood pressure, and will advise on treatment with Cialis Together or Viagra Connect, or the need to consult a GP. Pharmacies usually have a private room for such discussions.
Cialis Together is a 10mg tadalafil product for use at least 30 minutes prior to anticipated sexual activity. Its effects can last. It is not recommended for daily use. The maximum recommended dose of Cialis Together will be one tablet in 24 hours. Prescription Cialis and tadalafil will still be available at different doses.
Dr Fox welcomes the wider access to ED medication for men that Cialis Together classified as a ‘P’ OTC medication will provide. We at Dr Fox are aware of the difficulties men have in discussing ED with their GPs and in accessing ED medication. We know that Cialis is effective and safe for most men and this change provides another option for obtaining ED treatment. Pharmacists are health professionals who are able to give ED advice but they will also know when to refer men who would benefit from a doctor’s assessment. ‘P’ medicines can also be supplied on prescription, and we will offer Cialis Together, when available, alongside our other competitively priced ED products.
Dr Claire Pugh, Dr Fox Medical Director
In the UK have 3 categories:
The actor has been battling the severe side effects of a drug called sildenafil, which has been linked to severe erectile dysfunction.
But it's not just about erectile dysfunction.
Mick Jagger, who plays a doctor's assistant in the 2010 hit, told the British Medical Journal : "I feel very uncomfortable about it, especially when he's a patient, because it's not something I like to go down as."
Jagger also claimed that sildenafil was a "disaster" for a man who has never had an erection. The drug can cause a sudden drop in blood pressure, leading to dizziness and fainting.
Dr Fox, who has conducted a number of research studies on the side effects of sildenafil, has also revealed that his prescribing habits are inconsistent.
The Daily Mail quoted Dr Fox as saying: "I would rather have one drink before bed than to have to do anything about it."
The Daily Mail quoted Dr Fox as saying: "I would rather have one drink before bed than have to do anything about it."
A doctor's assistant in the 2010 hitMick Jagger took to social media to share what he had found in his sexual history.Mick Jagger was prescribed sildenafil for erectile dysfunction in 2010.
The actor said: "I'm just having a hard time getting the same treatment that I've been suffering with.
"Sildenafil is a medicine that has a number of side effects. The usual ones are lightheadedness, fainting, drowsiness, stomach cramps, and headache.
"The side effects are very rare, but if you have a very bad reaction to it it's very important that you contact a doctor right away and see if the problem is related to any other factors.
"In general, it's a very safe medicine to take, but you can get the same medicine through a different route or from someone else. It's important to talk to your doctor before you go down that road. There's no way of telling what you are going to be given to you."
Dr Fox also revealed that he has received multiple reports of erectile dysfunction, and that the medication has been linked to up to two thirds of all cases.
The Daily Mail quoted him as saying: "I've been dealing with this from the beginning, and it is a real shock. I've had some terrible side effects from the use of sildenafil. It's a real problem. You have people coming in with a sudden drop in blood pressure. But it can be quite a serious problem."
The Daily Mail quoted him as saying: "It's definitely a very scary situation. I'm not saying that I'm cures it all. But it can have serious consequences, and I'm not talking about that I had a heart attack."
In one post, he told Daily Mail that he had had four "very bad" sexual experiences in the past.
He also said he had "very painful headaches, a bad headache, a bad stomach upset, a bad memory, a bad headache and a bad mood."
Mick Jagger is thought to have taken Viagra on a regular basis, and that he had been taking the drug for a few years.
Mick Jagger had been prescribed sildenafil in 2010Mick Jagger was also taking Viagra on a regular basis, and that he had been taking the drug for a few years.
The Daily Mail quoted him as saying: "I have been using the drug for a few years and it's been helping me. I take it every day, not every day.
"But I have suffered with erectile dysfunction, and I have had to stop taking it.
"I have a lot of problems in my life. I had a terrible stroke in my life, and I had to stop taking it.
"I have a very bad heart attack a few years back. My doctor told me to stop it, because I wouldn't be able to go to my doctor. I've stopped taking it and I'm really struggling."
Mick Jagger was prescribed Viagra on a regular basis, and that he had been taking the drug for a few years.
The Daily Mail quoted him as saying: "I've been taking the drug for a few years and it's been helping me.
"But I have suffered with erectile dysfunction and I have had to stop taking it.
VIGRATION: The Food and Drug Administration has approved the first clinical trial to test the efficacy of sildenafil (Viagra®) as a treatment for erectile dysfunction (ED) in men.
Sildenafil is the generic name of the drug Viagra®. Viagra® is available in tablet form and it is a phosphodiesterase type 5 (PDE5) inhibitor. Viagra® is used to treat ED. Viagra® is the only ED drug that has received FDA approval in the United States for the treatment of PAH.
The clinical trial will be led by Dr. Steven Nissen and Dr. Richard A. Kocin of the University of Miami School of Medicine.
The primary objective of the study was to evaluate the effect of sildenafil (Viagra®) treatment on pulmonary arterial blood flow (PBAF), right ventricular pressure, and cardiac index in healthy men. The secondary objective was to evaluate the effects of sildenafil on cardiac output, which is a measure of cardiac performance, on the ability to exercise, and on the ability to perform a normal or moderately low workload.
Sildenafil was found to be as effective as Viagra® in increasing PBAF in healthy men. In a similar study, the effect of sildenafil on PBAF was also evaluated in men with heart disease.
Based on the results of this study, the FDA is requiring all FDA-approved drug products to include a written “black box” warning on their labels about the drug’s risk of serious cardiac damage and death, including heart failure, and it is anticipated that this warning will be updated in the coming months.
The trial will be conducted at the University of Miami School of Medicine. Researchers are also interested in enrolling men in clinical studies in men with ED. Researchers are also currently planning to enroll men in clinical studies in men with PAH.
VIDEOThis information is provided for general awareness and educational purposes only and is not intended to be a substitute for professional medical advice. Always consult your doctor or pharmacist for medical advice related to your health or medical conditions.
For more information on Viagra® and its use for ED, visit
Always consult your doctor for medical advice related to your health or medical conditions.
Sildenafil is available in the United States and is used to treat the following conditions:
In men, ED can be caused by a variety of physical causes, including:
Viagra® is not approved for the treatment of erectile dysfunction.
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